2-AMINO-BICYCLO[3.1.0]HEXANE-2,6-DICARBOXYLIC ACID DERIVATIVES AND A PROCESS FOR PREPARATION THEREOF

摘要

The present invention relates to the compound of formulae (see formula I-A)(see formula I-B)(see formula I-C) and to a novel process for the manufacture of compounds of the general formula (see formula I) wherein T is tritium; R1 is hydroxy, lower alkoxy, lower alkenyloxy, benzyloxy, hydrogen, deuterium or tritium; R11 is hydrogen, deuterium or optionally tritium, hydroxy or amino and R2 is hydrogen or optionally tritium or R1 and R2 form a bond. Compounds of general formula I are ligands for the metabotropic glutamate receptors of group II.