发明名称 1-ACETIC ACID-INDOLE DERIVATIVES WITH PGD2 ANTAGONIST ACTIVITY
摘要 Compounds of general formula (I) wherein R1 is halo or cyano; R2 is C1-C4 alkyl; and R3 is phenyl substituted with one or more substituents chosen from C1-C6 alkyl, halo or —SO2(C1-C6 alkyl); or a pharmaceutically acceptable salt, hydrate, solvate, complex or prodrug thereof; are useful in the treatment of diseases and conditions mediated by the action of PGD2 at the CRTH2 receptor.
申请公布号 US2010330077(A1) 申请公布日期 2010.12.30
申请号 US20060908401 申请日期 2006.03.10
申请人 OXAGEN LIMITED 发明人 ARMER RICHARD EDWARD;BOYD EDWARD ANDREW;HAY PHILIP ANDREW
分类号 A61K31/405;A61K31/404;A61K31/4164;A61K31/436;A61K31/4439;A61K31/4545;A61K31/47;A61K31/56;A61K39/395;A61P1/00;A61P1/04;A61P11/06;A61P17/00;A61P17/06;A61P17/10;A61P19/02;A61P25/16;A61P25/28;A61P37/00;A61P37/06;A61P37/08;C07D403/06;C07D403/14 主分类号 A61K31/405
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