发明名称 |
1-ACETIC ACID-INDOLE DERIVATIVES WITH PGD2 ANTAGONIST ACTIVITY |
摘要 |
Compounds of general formula (I) wherein R1 is halo or cyano; R2 is C1-C4 alkyl; and R3 is phenyl substituted with one or more substituents chosen from C1-C6 alkyl, halo or —SO2(C1-C6 alkyl); or a pharmaceutically acceptable salt, hydrate, solvate, complex or prodrug thereof; are useful in the treatment of diseases and conditions mediated by the action of PGD2 at the CRTH2 receptor.
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申请公布号 |
US2010330077(A1) |
申请公布日期 |
2010.12.30 |
申请号 |
US20060908401 |
申请日期 |
2006.03.10 |
申请人 |
OXAGEN LIMITED |
发明人 |
ARMER RICHARD EDWARD;BOYD EDWARD ANDREW;HAY PHILIP ANDREW |
分类号 |
A61K31/405;A61K31/404;A61K31/4164;A61K31/436;A61K31/4439;A61K31/4545;A61K31/47;A61K31/56;A61K39/395;A61P1/00;A61P1/04;A61P11/06;A61P17/00;A61P17/06;A61P17/10;A61P19/02;A61P25/16;A61P25/28;A61P37/00;A61P37/06;A61P37/08;C07D403/06;C07D403/14 |
主分类号 |
A61K31/405 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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