| 发明名称 |
COMPOSITIONS AND METHODS FOR TREATING COLLAGEN-MEDIATED DISEASES |
| 摘要 |
A drug product comprising a combination of highly purified collagenase I and collagenase II from Colostridium histolyticum is disclosed. The drug product includes collagenase I and collagenase II in a ratio of about 1 to 1, with a purity of greater than at least 95%. The invention further disclosed improved fermentation and purification processes for preparing the said drug product. |
| 申请公布号 |
US2010330065(A1) |
申请公布日期 |
2010.12.30 |
| 申请号 |
US20100837933 |
申请日期 |
2010.07.16 |
| 申请人 |
|
发明人 |
SABATINO GREGORY L.;DEL TITO, JR. BENJAMIN J.;BASSETT PHILLIP J.;THARIA HAZEL A.;HITCHCOCK ANTONY G.;YU BO;WEGMAN THOMAS L. |
| 分类号 |
A61K38/48;A61P17/02;A61P19/04 |
主分类号 |
A61K38/48 |
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