摘要 |
<p>The present invention relates to the use of peptide compounds for the prevention and/or treatment of ophthalmic diseases. In particular, the present invention relates to a peptide compound comprising an amino acid sequence displayed by amino acids 7 to 11 of SEQ ID NO: 2 ( KEQWFGNRWHEGYR ) or of SEQ ID NO: 1 (KEKWFENEWQGKNP), or a functionally active derivative thereof, or a pharmaceutically acceptable salt thereof, for use in the prevention and/or treatmend of an ophthalmic disease in an individual. While SEQ ID NO: 2 is a part of the human CD44v6, SEQ ID NO: 1 is a part of the rat CD44v6.</p> |
申请人 |
KARLSRUHER INSTITUT FUER TECHNOLOGIE;MATZKE, ALEXANDRA;PONTA, HELMUT;ORIAN-ROUSSEAU, VERONIQUE;TREMMEL, MARTINA |
发明人 |
MATZKE, ALEXANDRA;PONTA, HELMUT;ORIAN-ROUSSEAU, VERONIQUE;TREMMEL, MARTINA |