发明名称 |
3-SUBSTITUTED-8-SUBSTITUTED-3H IMIDAZO[5,1-D][1,2,3,5-TETRAZIN-4-ONE COMPOUNDS AND THEIR USE |
摘要 |
The present invention pertains generally to the field of therapeutic compounds, and more specifically to 3-substituted-8-substituted-3H-imidazo[5,1-d][1,2,3,5]tetrazin-4-one compounds of the following formula, wherein -A and -B are as defined herein (collectively referred to herein as 38TM compounds): (1). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit cell proliferation, and in the treatment of proliferative disorders such as cancer, etc., and methods of preparing such compounds. |
申请公布号 |
WO2010149968(A1) |
申请公布日期 |
2010.12.29 |
申请号 |
WO2010GB01233 |
申请日期 |
2010.06.23 |
申请人 |
PHARMINOX LIMITED;HUMMERSONE, MARC, GEOFFERY;STEVENS, MALCOLM, FRANCIS, GRAHAM;COUSIN, DAVID |
发明人 |
HUMMERSONE, MARC, GEOFFERY;STEVENS, MALCOLM, FRANCIS, GRAHAM;COUSIN, DAVID |
分类号 |
C07D487/04;A61K31/4188;A61K31/427;A61P35/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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