发明名称 NOVEL INDOLE, INDAZOLE AND BENZIMIDAZOLE ARYLAMIDES AS P2X3 AND/OR P2X2/3 ANTAGONISTS
摘要 Compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein, X, Y, Z, R1, R2, R3, R4 and R5 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptor antagonists and methods of making the compounds.
申请公布号 WO2010149634(A1) 申请公布日期 2010.12.29
申请号 WO2010EP58757 申请日期 2010.06.22
申请人 F. HOFFMANN-LA ROCHE AG;DILLON, MICHAEL PATRICK;KRAUSS, NANCY ELISABETH 发明人 DILLON, MICHAEL PATRICK;KRAUSS, NANCY ELISABETH
分类号 C07D401/04;A61K31/4439;A61K31/497;A61P1/04;A61P11/00;A61P13/00;A61P29/00;C07D401/14 主分类号 C07D401/04
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