发明名称 |
Synthetic human peptides and pharmaceutical compositions comprising them for the treatment of systemic lupus erythematosus |
摘要 |
Synthetic peptides of at least 12 and at most 30 amino acid residues comprising a sequence consisting of, or found within, a complementarity-determining region (CDR) found in the heavy or light chain of the human anti-DNA 16/6Id monoclonal antibody, or a sequence obtained by replacement and/or deletion and/or addition of one or more amino residues to said sequence, and salts, chemical derivatives and polymers of said peptides can be used for immunomodulation of systemic lupus erythematosus-associated responses.
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申请公布号 |
US7858738(B2) |
申请公布日期 |
2010.12.28 |
申请号 |
US20070894472 |
申请日期 |
2007.08.20 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO., LTD. |
发明人 |
MOZES EDNA |
分类号 |
A61K38/00;C12Q1/37;A61K38/04;A61K38/16;A61K39/00;A61P17/00;A61P29/00;A61P37/02;A61P37/06;A61P43/00;C07K;C07K7/00;C07K14/00;C07K16/18;C12P21/08 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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