METHOD OF INCREASING ACCURACY OF DETERMINING SEQUENCE OF AMINO ACID RESIDUES OF BIOPOLYMER BASED ON MASS-SPECTROMETRIC ANALYSIS DATA, COMPUTER SYSTEM

摘要

FIELD: chemistry. ^ SUBSTANCE: algorithm of comparing mass spectra with a genome database is applied repeatedly after updating the database with new records or after deleting records from the database or after replacing the database with a database composed of new records. Additional records are generated by making changes in the sequence of identified biopolymers which correspond to replacements, deletions, insertions and modifications of one or more amino acid residues. Present invention also relates to a computer system whose operation is based on the disclosed method. ^ EFFECT: high accuracy of identifying sequence of amino acid residues of a biopolymer. ^ 5 cl, 1 dwg, 1 ex