| 摘要 |
[Object] The main obj ect of the present invention is to provide a fibrosis inhibitor. [Solving Means] The present invention relates to a fibrosis inhibitor containing the heterocyclic derivative represented by the following general formula (1) or a pharmaceutically acceptable salt thereof as an active ingredient;
In the formula (1),
R 1 and R 2 are the same or different and each represents an optionally substituted aryl;
R 3 and R 4 are the same or different and each represents hydrogen atom or alkyl;
R 5 represents hydrogen atom, alkyl or halogen atom;
Y represents N or N†’O;
A represents NR 6 , and R 6 represents hydrogen atom, alkyl, etc.;
D represents alkylene or alkenylene which is optionally substituted with hydroxy;
E represents phenylene or a single bond;
G represents O, S, etc.; and Q represents carboxy, alkoxycarbonyl, etc. |
