CHALCONE COMPOUNDS AS ACTIVATORS OF DDAH PROMOTER FROM GLYCYRRHIZA URALENSIS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF ISLET CELLULAR APOPTOSIS AND DIABETIC NEPHROPATHY CONTAINING THE SAME AS AN ACTIVE INGREDIENT

摘要

PURPOSE: A composition containing Glycyrrhiza uralensis extract having chalcones is provided to increase DDAH(dimethylarginine dimethylaminohydrolase) activity and treat diabetic nephropathy. CONSTITUTION: A composition for preventing or treating pancreatic beta cell apoptosis and diabetic nephropathy contains Glycyrrhiza uralensis extract. The Glycyrrhiza uralensis extract is prepared by extracting Glycyrrhiza uralensis with ethanol solvent and concentrating. The Glycyrrhiza uralensis extract contains licochalcone F, echinantin, licochalcone D, licochalcone A, licoagrochalcone A, 5-prenylbutein or kanzonol C. A health food for preventing or treating pancreatic beta cell apoptosis and diabetic nephropathy contains Glycyrrhiza uralensis extract.