发明名称 |
METHOD FOR DETECTING NEOPLASTIC DISORDERS IN A SOLUBILIZED BODY SAMPLE |
摘要 |
The present invention relates to a method for the early diagnosis of carcinomas and their preliminary stages, which comprises determining the overexpression of a cell cycle regulatory protein in a solubilized body sample. The present invention is particularly directed to a method for detecting cervical carcinomas, cervical intraepithelial neoplasias, or cervical carcinomas in-situ from a solubilized cervical body sample of a human subject, by solubilizing the cervical body sample in a lysis buffer, and determining the overexpression of cyclin dependent kinase inhibitor p16 in the solubilized cervical sample. The invention also concerns a test kit usable for this purpose as well as an in-vitro diagnostic device. |
申请公布号 |
HK1092219(A1) |
申请公布日期 |
2010.12.24 |
申请号 |
HK20060113997 |
申请日期 |
2006.12.20 |
申请人 |
MTM LABORATORIES AG |
发明人 |
RIDDER, RUEDIGER;REICHERT, ANJA;VON KNEBEL DOEBERITZ, MAGNUS;HERKERT, MATTHIAS;DUWE, ALEXANDER;HIPFEL, RAINER;MARTIN, PETER |
分类号 |
G01N;G01N33/574 |
主分类号 |
G01N |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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