| 摘要 |
PROBLEM TO BE SOLVED: To provide a novel method of treating asthma. SOLUTION: This method comprises administration of an antibody recognizing VLA-4, a polypeptide or other molecules for example, a protein developed on the surface of a certain kind of white blood cell, such as an acidocyte. This invention provides a method comprising a process administrating an effective amount of an anti-VLA-4 antibody, for example, a monoclonal antibody HP1/2 to a patient of asthma. The anti-VLA-4 antibody is advantageously administered in vivo to a patient having chronic allergen induced asthma and prevents late-reaction to allergen and at the same time alleviates airway hyperactivity. COPYRIGHT: (C)2011,JPO&INPIT
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