摘要 |
PROBLEM TO BE SOLVED: To provide an industrially advantageous method for producing aminopyridines in a higher yield in comparison with a conventional method of production. SOLUTION: In the method for producing aminopyridines by heating halopyridines represented by formula (1) (wherein R is perfluoroalkyl; and X is a halogen atom with the proviso that X is not present at the 3-position or 5-position of the pyridine ring) and an ammonia solution in the absence of a catalyst and reacting the halopyridines with ammonia to produce the aminopyridines represented by formula (2) (wherein R is as shown above; and the amino group is not present at the 3-position or 5-position of the pyridine ring), the ammonia concentration of the ammonia solution is≥35 wt.% and the reaction is a heterogeneous reaction. COPYRIGHT: (C)2011,JPO&INPIT |