发明名称 Heterocyclic piperazine-carboxamide compounds as CCR2B antagonists
摘要 Piperazin-carbonyl-piperazine-carboxamide derivatives of formula (Ia) and pharmaceutically acceptable salts or solvates thereof are disclosed, wherein the variables are as defined in the specification. These compounds are useful in the treatment of C-C chemokine mediated conditions selected from asthma, allergic rhinitis, COPO, inflammatory bowel disease, irritable bowel syndrome, osteoarthritis, osteoporosis, rheumatoid arthritis, and psoriasis.
申请公布号 NZ555770(A) 申请公布日期 2010.12.24
申请号 NZ20050555770 申请日期 2005.12.19
申请人 ASTRAZENECA AB 发明人 BOWER, JUSTIN FAIRFIELD;POYSER, JEFFREY PHILIP;TURNER, PAUL;WATERSON, DAVID;WINTER, JON
分类号 A61K31/497;A61P29/00;A61P31/18;A61P35/00;C07D211/26;C07D295/20;C07D295/215;C07D401/04;C07D401/06;C07D401/08;C07D401/12 主分类号 A61K31/497
代理机构 代理人
主权项
地址