| 摘要 |
Compound (A) that contains: (a) a carrier (C) with at least two functional groups; and bound to (a) (b) at least one (un)saturated hydrocarbyl or acyl residue; and (c) a residue that comprises a group (I) and an anchor group (AG). Compound (A) that contains: (a) a carrier (C) with at least two functional groups; and bound to (a) (b) at least one (un)saturated hydrocarbyl or acyl residue with chain length 10-22C, optionally substituted by one or more side groups; and (c) a residue that comprises a group (CH2CH2O)n (I) and an anchor group (AG). n = 1-100. Independent claims are also included for: (1) new compounds of formula (Ia) or (Ib); and (2) a supported biomimetic membrane (M) comprising a lipid layer containing at least one (A) as support lipid for anchoring to a substrate. R1 and R2 = (un)saturated hydrocarbyl or acyl with 10-22C chains, optionally substituted by one or more sidechains, hydrogen, 1-9C hydrocarbyl, or a residue comprising a phospholipid, carboxy, carbonyl, sulfinyl, sulfonyl, amido, amino or thiol group, with or without 1-9C hydrocarbyl; n = 1-100; R3 = residue containing an anchoring group; X = linking group; and provided that at least one of R1 and R2 is (un)saturated hydrocarbyl or acyl with 10-22C chains, optionally substituted by one or more sidechains. |
