SUBSTITUTED ISOQUINOLINE DERIVATIVE

摘要

Disclosed is an isoquinoline-6-sulfonamide derivative which is useful as a novel medicinal agent. Specifically disclosed is an isoquinoline-6-sulfonamide derivative represented by general formula (1) (wherein X and Y independently represent a direct bond, NH, CH=CH, O or S; R1 and R2 independently represent a hydrogen atom, a halogen atom, a cyano group, an alkyl group, or the like; R3 and R4 independently represent a hydrogen atom, an alkyl group, or the like, or R3 and R4 may together form an alkylene group or an alkenylene group and two carbon atoms at any positions in R3 and R4 may be crosslinked; and l, m and n independently represent a numeral value of 1 to 4), a salt of the derivative, or a solvate of the derivative or the salt.