发明名称 |
EYE-DROP PREPARATION AND USE THEREOF |
摘要 |
Disclosed is a technique for preventing the decomposition of latanoprost (a thermally unstable substance) contained in an eye-drop solution to stabilize the eye-drop solution. Specifically disclosed is an eye-drop preparation comprising latanoprost and carteolol hydrochloride. By adding carteolol hydrochloride to an eye-drop solution containing latanoprost which is a thermally unstable substance and is likely to be adhered on the surface of a container, it becomes possible to prevent the decomposition of latanoprost in the eye-drop solution and also prevent the loss of latanoprost caused by the adsorption of latanoprost on the surface of a container. |
申请公布号 |
KR20100134682(A) |
申请公布日期 |
2010.12.23 |
申请号 |
KR20107023457 |
申请日期 |
2009.04.23 |
申请人 |
OTSUKA PHARMACEUTICAL CO., LTD. |
发明人 |
ONISHI YOSHINAO;ISHIKAWA SHINICHI |
分类号 |
A61K31/5575;A61K31/4704;A61P27/06;A61P43/00 |
主分类号 |
A61K31/5575 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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