FUSION PROTEINS THE PROCESS TO PREPARATION AND UTILIZATION IN EXPRESSION SYSTEMS OF RECOMBINANT PROTEINS

摘要

The present application relates to improved recombinant protein production processes through the use of novel fusion tags. In particular, the present application discloses novel fused proteins comprising an aminoacidic sequence that corresponds to a fragment H or an aminoacidic sequence that corresponds to a calcium-binding protein excreted/secreted by the adult worm of Fasciola hepatisa, namely, Fh8 and Fh22 proteins, followed by an aminoacidic sequence that corresponds to a non-related protein fragment or protein, and methods for its preparation and its use thereof.