| 发明名称 |
PYRROLOPYRIDINE DERIVATIVES AND THEIR USE AS BACE INHIBITORS |
| 摘要 |
This invention relates to novel compounds having the structural formula I below: (I) and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.
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| 申请公布号 |
US2010324072(A1) |
申请公布日期 |
2010.12.23 |
| 申请号 |
US20080600177 |
申请日期 |
2008.05.14 |
| 申请人 |
ASTRAZENECA AB;ASTEX THERAPEUTICS LTD. |
发明人 |
CHESSARI GIANNI;CONGREVE MILES STUART;HOLENZ JORG;MURRAY CHRISTOPHER;PATEL SAHIL;RAKOS LASZLO;ROTTICCI DIDIER |
| 分类号 |
A61K31/506;A61K31/437;A61P25/00;A61P25/16;A61P25/28;C07D471/04 |
主分类号 |
A61K31/506 |
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