发明名称 |
PRODUCTION OF VIRAL CAPSIDS |
摘要 |
The invention provides methods of producing "empty" RNA virus capsids (e.g. from Cowpea mosaic virus) by assembly of viral small (S) and large (L) coat proteins in such a way that encapsidation of native viral RNA is avoided. Aspects of the invention employ in planta expression of capsid components from DNA vectors encoding the S and L proteins or S-L polyproteins including them. Such capsids have utility for the encapsidation or presentation of foreign proteins or desired payloads.
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申请公布号 |
CA2765357(A1) |
申请公布日期 |
2010.12.23 |
申请号 |
CA20102765357 |
申请日期 |
2010.06.15 |
申请人 |
PLANT BIOSCIENCE LIMITED |
发明人 |
SAUNDERS, KEITH;LOMONOSSOFF, GEORGE PETER;SAINSBURY, FRANK |
分类号 |
C12N15/82;C07K14/08;C12N7/04 |
主分类号 |
C12N15/82 |
代理机构 |
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地址 |
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