发明名称 |
Targeted modification of chromatin structure |
摘要 |
Methods and compositions for targeted modification of chromatin structure, within a region of interest in cellular chromatin, are provided. Such methods and compositions are useful for facilitating processes such as, for example, transcription and recombination, that require access of exogenous molecules to chromosomal DNA sequences.
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申请公布号 |
US2010323424(A1) |
申请公布日期 |
2010.12.23 |
申请号 |
US20100803927 |
申请日期 |
2010.07.09 |
申请人 |
SANGAMO BIOSCIENCES, INC. |
发明人 |
WOLFFE ALAN P.;WOLFFE ELIZABETH J.;COLLINGWOOD TREVOR;GREGORY PHILIP D.;SNOWDEN ANDREW;URNOV FYODOR |
分类号 |
C12N9/14;C07H21/00;C07K14/47;C12N5/07;C12N5/10;C12N9/00;C12N9/10;C12N9/78;C12N15/10;C12N15/62;C12N15/63;C12N15/66;C12N15/67;C12Q1/68;G06F19/22;G06F19/28 |
主分类号 |
C12N9/14 |
代理机构 |
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代理人 |
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