METHODS AND MARKERS FOR PREDICTING RESPONSES TO CHEMOTHERAPY

摘要

The present invention provides methods for determining or predicting the sensitivity and/or resistance of breast tumors to taxane therapy, including ER- breast tumors that may otherwise be considered good candidates for taxane therapy. By discriminating taxane-resistant and taxane-sensitive tumors, even within the ER- population, the present invention allows a treating physician to select more effective chemotherapeutic regimens and/or spare the patient from unnecessary toxicity.