发明名称 |
ADULT CEREBELLUM-DERIVED NEURAL STEM CELLS AND COMPOSITIONS AND METHODS FOR PRODUCING OLIGODENDROCYTES |
摘要 |
This disclosure describes a novel population of cerebellum-derived neural stem cells that can be isolated from the adult brain, expanded, and differentiated into neurons, astrocytes and oligodendrocytes. This disclosure also describes compositions and methods for producing oligodendrocytes. Oligodendrocytes can be produced in vitro (e.g., in culture) or in vivo (e.g., for therapy or in a non-human transgenic animal) using the compositions and methods described herein. |
申请公布号 |
WO2010147803(A2) |
申请公布日期 |
2010.12.23 |
申请号 |
WO2010US37789 |
申请日期 |
2010.06.08 |
申请人 |
REGENTS OF THE UNIVERSITY OF MICHIGAN;O'SHEA, KATHY, SUE;MORELL, MARIA |
发明人 |
O'SHEA, KATHY, SUE;MORELL, MARIA |
分类号 |
C12N5/0797;A61K35/30;A61P25/00;C07K14/47 |
主分类号 |
C12N5/0797 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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