发明名称 |
Compositions and Methods for Controlling Copy Number for a Broad Range of Plasmids and Uses Thereof |
摘要 |
The present invention provides compositions and methods for controlling the copy number for a broad range of plasmids and uses thereof. Disclosed is a host cell for conditional control of copy number of a plasmid, which host cell comprises a poly(A) polymerase gene that is operably joined to a conditionally inducible promoter, and a method for cloning and stably maintaining a DNA sequence encoding a heterologous polypeptide in the host cell.
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申请公布号 |
US2010323400(A1) |
申请公布日期 |
2010.12.23 |
申请号 |
US20100837466 |
申请日期 |
2010.07.15 |
申请人 |
HASKINS DARIN J;HOFFMAN LESLIE M |
发明人 |
HASKINS DARIN J.;HOFFMAN LESLIE M. |
分类号 |
C12P21/00;C12N1/21;C12P19/34 |
主分类号 |
C12P21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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