| 发明名称 |
COVALENTLY BINDING IMAGING PROBES |
| 摘要 |
<p>The present invention relates to molecular probes of the formula (I) L1-R1-L-A-X (I) as defined herein that allow for the observation of the catalytic activity of a selected caspase, cathepsin, MMP and carboxypeptidase in in vitro assays, in cells or in multicellular organisms, a method for their preparation and the use thereof.</p> |
| 申请公布号 |
EP2262783(A2) |
申请公布日期 |
2010.12.22 |
| 申请号 |
EP20090711894 |
申请日期 |
2009.02.06 |
| 申请人 |
SANOFI-AVENTIS |
发明人 |
WENDT, KARL-ULRICH;KINDERMANN, MAIK;MINIEJEW, CATHERINE;GLOBISCH, ANJA |
| 分类号 |
C07D277/42;A61K31/495;C07D403/12;C07D413/12 |
主分类号 |
C07D277/42 |
| 代理机构 |
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