发明名称 Plasmodium liver stage antigens
摘要 The invention provides isolated liver stage Plasmodium polypeptides comprising an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-48 and immunogenic derivatives thereof. The invention also provides isolated nucleic acid molecules encoding the liver stage Plasmodium polypeptides of the invention, compositions comprising one or more liver stage Plasmodium polypeptides of the invention, methods for inducing an immune response against the liver stage Plasmodium polypeptides, and methods for treating and diagnosing liver stage malaria.
申请公布号 EP2264058(A2) 申请公布日期 2010.12.22
申请号 EP20100171776 申请日期 2006.09.29
申请人 THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY, ON BEHALF OF THE WALTER REED ARMY INSTITUTE OF RESEARCH;SEATTLE BIOMEDICAL RESEARCH;PHILADELPHIA HEALTH AND EDUCATION CORPORATION 发明人 DUFFY, PATRICK;KAPPE, STEFAN H.I.;KRZYCH, URSZULA;HEPPNER, DONALD G.;BERGMAN, LAWRENCE W.;MALKOV, VLADISLAV A.;TARUN, ALICE;WENDLER, JASON P.;BACIK, IGOR
分类号 C07K14/445 主分类号 C07K14/445
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