| 摘要 |
<p>A method of producing an optically active cyanohydrin compound represented by formula (3)
(wherein, Q 1 and Q 2 are as defined below, and * represents that the indicated carbon atom is the optically active center) comprising reacting an aldehyde compound represented by formula (2)
(wherein, Q 1 and Q 2 represent each independently a hydrogen atom, optionally substituted alkyl group having 1 to 6 carbon atoms, or the like) with hydrogen cyanide in the presence of a silyl compound and an asymmetric complex which is obtained by reacting an optically active pyridine compound represented by formula (1)
(wherein, R 1 and R 2 represent each independently a hydrogen atom, alkyl group having 1 to 6 carbon atoms, or the like, provided that R 1 and R 2 are not the same.) with an aluminum halide.</p> |
