| 发明名称 |
COMPOUNDS AND PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR |
| 摘要 |
Peptides of 10 to 40 or more amino acid residues in length and having the sequence X3X4X5GPX6TWX7X8(SEQ ID NO:) where each amino acid is indicated by standard one letter abbreviation; X3 is C; X4 is R, H, L, or W; X5 is M, F, or I; X6 is independently selected from any one of the 20 genetically coded L-amino acids; X7 is D, E, I, L, or V; and X8 is C, which bind and activate the erythropoietin receptor (EPO-R) or otherwise act as an EPO agonist, and methods for their use.
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| 申请公布号 |
CA2223833(C) |
申请公布日期 |
2010.12.21 |
| 申请号 |
CA19962223833 |
申请日期 |
1996.06.07 |
| 申请人 |
AFFYMAX TECHNOLOGIES N.V.;ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
WRIGHTON, NICHOLAS C.;DOWER, WILLIAM J.;CHANG, RAY S.;KASHYAP, ARUN K.;JOLLIFFE, LINDA K.;JOHNSON, DANA;MULCAHY, LINDA |
| 分类号 |
A61K38/22;C07K7/08;A61K38/00;A61K38/08;A61K38/10;A61K38/12;A61K38/16;A61K38/18;A61P7/06;C07K7/06;C07K7/54;C07K14/00;C07K14/505 |
主分类号 |
A61K38/22 |
| 代理机构 |
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