METHOD FOR PREDICTION OF RISK OF DEVELOPMENT OF SEVERE HEMORRHAGIC FEVER WITH RENAL SYNDROME

摘要

FIELD: medicine. ^ SUBSTANCE: invention refers to medicine, namely to infectious diseases, and can be used for prediction of the risk of development of severe hemorrhagic fever with renal syndrome. DNA is recovered from lymphocytes of peripheral venous blood; PCR-analysis of CYP1A1 and GSTP1 polymorphic loci follows. If observing heterozygous genotype AG of GSTP1 gene or combined 1A2C/AG genotypes of CYP1A1 and GSTP1 genes, the high risk of development of severe HFRS is predicted. ^ EFFECT: invention provides a precise prediction of development of severe disease. ^ 5 tbl, 2 ex