发明名称 METHODS FOR ADMINISTRATION OF 3-(4-AMINO-1-OXO-1,3-DIHYDROISOINDOLE-2-YL)PIPERIDINE-2,6-DIONE IN CERTAIN TYPES OF LEUKEMIA
摘要 FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention refers to medicine, namely to oncology, and can be used in leukemia treatment. The methods involve the course introduction of 3-(4-amino- 1-oxo-1,3-dihydroisoindole-2-yl) piperidine-2,6-dione 5 to 50 mg a day. Also the method under the invention involves the introduction of 3-(4-amino- 1-oxo-1,3-dihydroisoindole-2-yl) piperidine-2,6-dione with the second active agent. ^ EFFECT: use of the invention allows higher clinical effectiveness for leukemia ensured by the introduction of specified level doses of 3-(4-amino- 1-oxo-1,3-dihydroisoindole-2-yl) piperidine-2,6-dione which enable the inhibition of tumour cell proliferation and exhibit low toxicity. ^ 22 cl, 2 tbl, 5 ex
申请公布号 RU2406501(C2) 申请公布日期 2010.12.20
申请号 RU20080117432 申请日期 2006.10.03
申请人 SELDZHIN KORPOREJSHN 发明人 ZELDIS DZHEROM B.
分类号 A61K31/00;A61K31/40;A61K31/425;A61K31/445;A61K31/454;A61K31/515;A61K45/06;A61P35/00 主分类号 A61K31/00
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