发明名称 COMPOSITIONS OF PEPTIDE CONJUGATE AND METHODS FOR PREVENTION AND TREATMENT OF ALZHEIMER'S DISEASE
摘要 FIELD: medicine. ^ SUBSTANCE: invention relates to biotechnology and represents pharmaceutical compositions and method for treatment of diseases associated with amyloid depositions A in patient's brain, such as Alzheimer's disease. Method includes introduction of immunogenic fragment A with absence of T-cell epitope, able to induce effective immune response in form of antibodies to A. Pharmaceutical compositions include immunogenic fragment, chemically bound with carrier molecule, which can be introduced with adjuvant. ^ EFFECT: invention is efficient as vaccine against Alzheimer's disease. ^ 18 cl, 13 dwg, 9 tbl, 10 ex
申请公布号 RU2406529(C2) 申请公布日期 2010.12.20
申请号 RU20070145052 申请日期 2006.05.01
申请人 MERK SHARP EHND DOMEH KORP. 发明人 GARSKI VIKTOR M.;DZHOJS DZHOZEF DZH.;KELLER POL M.;KINNI DZHIN;LJAN SJAOPIN;SHIVER DZHON V.
分类号 A61K38/04;A61K39/00;A61P43/00 主分类号 A61K38/04
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