| 发明名称 |
1-BENZYL-3-HYDROXYMETHYLINDAZOLE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF DISEASES BASED ON THE EXPRESSION OF MCP-1 AND CX3CR1 |
| 摘要 |
The present invention relates to novel 1-benzyl-3-hydroxymethylindazole derivatives according to formula (I) described in the claims, and to a pharmaceutical composition comprising them, together with a pharmaceutically acceptable vehicle. In addition, the present invention relates to the use of novel 1-benzyl-3-hydroxymethylindazole derivatives for the preparation of a pharmaceutical composition that is active in the treatment of diseases based on the expression of MCP-1 and CX3CR1, and to their use in a method for treating or preventing diseases based on the expression of MCP-1 and CX3CR1.
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| 申请公布号 |
US2010317618(A1) |
申请公布日期 |
2010.12.16 |
| 申请号 |
US20090866814 |
申请日期 |
2009.03.06 |
| 申请人 |
AZIENDE CHIM. RIUN. ANGEL. FRA. A.C.R.A.F. S.P.A. |
发明人 |
GUGLIELMOTTI ANGELO;FURLOTTI GUIDO;MANGANO GIORGINA;CAZZOLLA NICOLA |
| 分类号 |
A61K31/416;A61K31/4439;A61K31/454;A61K31/4545;A61K31/496;A61K31/522;A61K31/5377;A61K31/7008;A61P3/00;A61P3/04;A61P3/10;A61P9/00;A61P9/10;A61P19/02;A61P25/28;A61P35/00;A61P35/04;C07D231/56;C07D401/12;C07D413/12 |
主分类号 |
A61K31/416 |
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