发明名称 |
MALEIMID-DERIVATE, PHARMAZEUTISCHE ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG VON KREBS |
摘要 |
The present invention relates to pyrroloquinolinyl-pyrrole-2,5-dione compounds and pyrroloquinolinyl-pyrrolidine-2,5-dione compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrroloquinolinyl-pyrrole-2,5-dione compounds and pyrroloquinolinyl-pyrrolidine-2,5-dione compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or pyrroloquinolinyl-pyrrolidine-2,5-dione compound of the present invention. |
申请公布号 |
DE602006017965(D1) |
申请公布日期 |
2010.12.16 |
申请号 |
DE20066017965T |
申请日期 |
2006.02.09 |
申请人 |
ARQULE INC. |
发明人 |
LI, CHIANG J;ASHWELL, MARK ANTONY;HILL, JASON;MOUSSA, MAGDI M.;MUNSHI, NERU |
分类号 |
C07D471/06;A61K31/473;A61K31/551;A61K31/661;A61P35/00;C07D487/06;C07F9/12 |
主分类号 |
C07D471/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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