发明名称 RADIOLABELED HEDGEHOG DERIVATIVES FOR IMAGING AND THERAPY
摘要 The present invention concerns methods and compositions related to a chelator and a HHRT ligand. In specific embodiments of the invention the chelator is conjugated to the HHRT ligand. In another specific embodiment of the invention, the chelator is chelated to a metal. In a particular embodiment of the invention, there is a metal species that is chelated to a chelator, which is then directly or indirectly conjugated to a HHRT ligand. In some embodiments, the composition further comprises a therapeutic agent. In particular cases, the compositions are employed for cancer diagnosis and/or therapy.
申请公布号 US2010316566(A1) 申请公布日期 2010.12.16
申请号 US20090918443 申请日期 2009.02.27
申请人 RADIOMEDIX INC. 发明人 SIMS-MOURTADA JENNIFER;AZHDARINIA ALI;TWOROWSKA IZABELA;SASO HITOMI
分类号 A61K51/00;A61K33/24;A61K33/26;A61K33/36;A61K49/00;A61P35/04 主分类号 A61K51/00
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