METHOD, COMPOSITION AND LIBRARY RELATING TO PNA DIMER AND PNA OLIGOMER SYNTHESIS

摘要

PROBLEM TO BE SOLVED: To provide a method, composition and library relating to a PNA dimer and PNA oligomer.

SOLUTION: The invention relates to a field of PNA dimers and PNA oligomers. It discloses a solid support composition. The solid support composition is (a) an acid-forming cleavable linker and (b) a PNA dimer including a base labile N-terminal protecting group bound to the solid support by the cleavable linker in a cleavable manner wherein the loading of the PNA dimer on the solid support is≥0.08 mmol per one gram.

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