SEMICONDUCTOR BIOSENSORS

摘要

The present invention relates to semiconductor devices, in particular to a device for monitoring a cell signal such as an electrical signal produced by living cells in response to external stimulation, optionally in real time, comprising (a) at least one discrete area comprising a high electron mobility transistor (HEMT); and (b)non-excitable cells attached to said HEMT (HEMT element). Preferably, said device, and preferably said at least one discrete area which comprises a HEMT, has a surface suitable for cell attachment or growth. Accordingly, the device can be applied in uses and methods for monitoring a cell signal such as an electrical signal produced by living cells in response to external stimulation, optionally in real time. Likewise, the device can be applied for screening compounds that reverse, protect from and/or shield cells from external stimuli which cause damage to cells. Also, kits comprising the device are an aspect of the present invention.