| 发明名称 |
SMALL MOLECULE INHIBITORS OF MDM2 AND THE USES THEREOF |
| 摘要 |
The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth, inducing cell death, inducing cell cycle arrest and/or sensitizing cells to additional agent(s).
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| 申请公布号 |
US2010317661(A1) |
申请公布日期 |
2010.12.16 |
| 申请号 |
US20100815113 |
申请日期 |
2010.06.14 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
WANG SHAOMENG;QIN DONGGUANG;CHEN JIANYONG;YU SHANGHAI |
| 分类号 |
A61K31/5377;A61K31/407;A61K31/4178;A61K31/496;A61P1/00;A61P17/14;A61P35/00;C07D487/10;C12N5/00 |
主分类号 |
A61K31/5377 |
| 代理机构 |
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