DIFFERENT SEROTYPES OF VESICULAR STOMATITIS VIRUS AS EXPRESSION VECTORS FOR IMMUNIZATION REGIMENS

摘要

Immunization platforms, immunization regimes and medicaments useful for inducing an immune response in a mammal and preventing or treating a pathogenic infection in a mammal, wherein said immunization platforms and medicaments comprise a recombinant vesicular stomatitis virus (VSV) of one serotype and a rVSV of another serotype and are used in a prime-boost immunization regime In aspects of the invention one VSV serotype is Indiana and the other VSV serotype is New Jersey.