发明名称 |
SUBSTITUTED N-[1-CYANO-2-(PHENYL)ETHYL]PIPERIDIN-2-YLCARBOXMIDE COMPOUNDS 761 |
摘要 |
<p>The present invention provides a compound: (S)-N-((S)-1-Cyano-2-(4-(1-methyl-2-oxoindolin-6-yl)phenyl)ethyl)piperidine-2- carboxamide; (S)-N-((S)-1-Cyano-2-(4-(3-(3-methoxypropyl)-2-oxo-2,3-dihydrobenzo[d]oxazol-5- yl)phenyl)ethyl)piperidine-2-carboxamide; (S)-N-((S)-1-Cyano-2-(4'-(ethylsulfonyl)biphenyl-4-yl)ethyl)piperidine-2-carboxamide; 4'-((S)-2-Cyano-2-((S)-piperidine-2-carboxamido)ethyl)biphenyl-4-yl methanesulfonate; or, (S)-N-((S)-1-Cyano-2-(4-(1-oxoisoindolin-5-yl)phenyl)ethyl)piperidine-2-carboxamide; or a pharmaceutically acceptable salt thereof; a process for its preparation, pharmaceutical compositions containing it and its use in therapy.</p> |
申请公布号 |
WO2010142985(A1) |
申请公布日期 |
2010.12.16 |
申请号 |
WO2010GB50964 |
申请日期 |
2010.06.09 |
申请人 |
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;METE, ANTONIO |
发明人 |
METE, ANTONIO |
分类号 |
A61K31/4402;A61K31/4439;A61P11/00;C07D211/36;C07D401/12;C07D413/12 |
主分类号 |
A61K31/4402 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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