发明名称 |
METHODS AND COMPOSITIONS FOR ENHANCING DELIVERY OF DOUBLE-STRANDED RNA OR A DOUBLE-STRANDED HYBRID NUCLEIC ACID TO REGULATE GENE EXPRESSION IN MAMMALIAN CELLS |
摘要 |
A delivery-enhancing peptide comprising the amino acid sequence of SEQ ID NO:11 or salt thereof. This invention is directed towards methods and compositions to administer a double-stranded ribonucleic acid to a mammal so as to effectuate transfection of the double-stranded RNA into a desired tissue of the mammal.
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申请公布号 |
US2010316707(A1) |
申请公布日期 |
2010.12.16 |
申请号 |
US20100870989 |
申请日期 |
2010.08.30 |
申请人 |
MDRNA, INC. |
发明人 |
AHMADIAN MOHAMMAD;CUI KUNYUAN;CHEN LISHAN;CHEN SHU-CHIH;HOUSTON, JR. MICHAEL E. |
分类号 |
A61K38/16;A61K9/127;A61P43/00;C07K9/00;C07K14/00;C12N15/11;C12N15/113;C12N15/87 |
主分类号 |
A61K38/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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