发明名称 METHODS AND COMPOSITIONS FOR ENHANCING DELIVERY OF DOUBLE-STRANDED RNA OR A DOUBLE-STRANDED HYBRID NUCLEIC ACID TO REGULATE GENE EXPRESSION IN MAMMALIAN CELLS
摘要 A delivery-enhancing peptide comprising the amino acid sequence of SEQ ID NO:11 or salt thereof. This invention is directed towards methods and compositions to administer a double-stranded ribonucleic acid to a mammal so as to effectuate transfection of the double-stranded RNA into a desired tissue of the mammal.
申请公布号 US2010316707(A1) 申请公布日期 2010.12.16
申请号 US20100870989 申请日期 2010.08.30
申请人 MDRNA, INC. 发明人 AHMADIAN MOHAMMAD;CUI KUNYUAN;CHEN LISHAN;CHEN SHU-CHIH;HOUSTON, JR. MICHAEL E.
分类号 A61K38/16;A61K9/127;A61P43/00;C07K9/00;C07K14/00;C12N15/11;C12N15/113;C12N15/87 主分类号 A61K38/16
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