发明名称 |
Method of Determining the Probability of a Therapeutic Response in Cancer Chemotherapy With Cardiac Glycoside |
摘要 |
A prognostic assay and kit and method of use thereof are provided. The kit and assay are used to determine the likelihood of a diseased cell or tissue having a therapeutic response to treatment with a cardiac glycoside in a disease having an etiology associated with excessive cell proliferation. The kit and assay are used to determine the ratio of isoforms of the α subunit of Na, K-ATPase obtained from the diseased cell or tissue. The kit can be used to predict the therapeutic responsiveness of cancer or tumor in a subject to treatment with a cardiac glycoside. The kit and assay can be incorporated in a method of treating a disease or disorder having an etiology associated with excessive cell proliferation with a composition comprising a cardiac glycoside. |
申请公布号 |
US2010317541(A1) |
申请公布日期 |
2010.12.16 |
申请号 |
US20100773540 |
申请日期 |
2010.05.04 |
申请人 |
PHOENIX BIOTECHNOLOGY, INC. |
发明人 |
ADDINGTON OTIS CRANDELL;NEWMAN ROBERT A.;YANG PEIYING |
分类号 |
C40B30/04;C12Q1/34;C12Q1/68;G01N33/573 |
主分类号 |
C40B30/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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