| 发明名称 |
COMPSTATIN ANALOG WITH IMPROVED ACTIVITY |
| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide compounds comprising peptides and peptidomimetics capable of binding the C3 protein and inhibiting complement activation. <P>SOLUTION: Peptides with specific sequences, expressing improved complement activation-inhibitory activity as compared with currently available compounds, and compounds having partial peptidomimetics of the peptides are provided. Isolated nucleic acid molecules encoding the peptides are also provided. <P>COPYRIGHT: (C)2011,JPO&INPIT</p> |
| 申请公布号 |
JP2010280688(A) |
申请公布日期 |
2010.12.16 |
| 申请号 |
JP20100171021 |
申请日期 |
2010.07.29 |
| 申请人 |
TRUSTEES OF THE UNIV OF PENNSYLVANIA |
发明人 |
LAMBRIS JOHN D |
| 分类号 |
C07K7/08;A61K38/00;A61K38/08;A61K38/10;A61K38/16;A61P9/00;A61P11/00;A61P17/02;A61P37/06;A61P43/00;C07K14/47;C12N1/15;C12N1/19;C12N1/21;C12N15/09 |
主分类号 |
C07K7/08 |
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