发明名称 |
METHOD FOR DETERMINING PROTEIN-NUCLEIC ACID INTERACTION |
摘要 |
<p>The present invention refers to a method of determining protein-nucleic acid interaction. The method comprises mixing a protein with a sample comprising a nucleic acid which is suspected to interact with the protein to form a first mixture. The first mixture can be incubated to allow interaction between the protein and nucleic acid. Metallic nanoparticles are added to the first mixture to obtain a second mixture. An electrolyte is added to the first or second mixture to determine the protein-nucleic acid interaction. The present invention also refers to a kit for determining protein-nucleic acid interaction. The kit comprises a protein capable of interacting with a nucleic acid or a nucleic acid capable of interacting with a protein, and at least one type of metallic nanoparticle.</p> |
申请公布号 |
WO2010144053(A1) |
申请公布日期 |
2010.12.16 |
申请号 |
WO2010SG00196 |
申请日期 |
2010.05.27 |
申请人 |
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH;TAN, YEN NEE;SU, XIAODI |
发明人 |
TAN, YEN NEE;SU, XIAODI |
分类号 |
G01N33/53;C12Q1/68 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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