CHIMÄRER IMPFSTOFF FÜR HAEMOPHILUS INFLUENZAE- INDUZIERTE INFEKTION

摘要

The invention described herein relates to a chimeric protein comprising the NTHi twitching pilus major subunit protein (pilA) presenting a portion of the NTHi OMP P5 protein. The invention provides for vaccine compositions comprising the recombinant chimeric protein and methods of eliciting an immune response using the recombinant chimeric proteins of the invention.