发明名称 |
ANTIDIABETIC BICYCLIC COMPOUNDS |
摘要 |
Diaryl ethers in which one of the aryl groups is a phenyl fused to a cycloalkyl or heterocyclic ring, to which is attached an acetic acid group, are agonists of G-protein coupled receptor 40 (GPR40) and are useful as therapeutic compounds, particularly in the treatment of Type 2 diabetes mellitus, and of conditions that often accompany this disease, including insulin resistance, obesity and lipid disorders. |
申请公布号 |
EP2079467(A4) |
申请公布日期 |
2010.12.15 |
申请号 |
EP20070839789 |
申请日期 |
2007.10.26 |
申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
GE, MIN;LIN, SONGNIAN;WALSH, SHAWN P.;YANG, LIHU;ZHOU, CHANGYOU |
分类号 |
A61K31/426;A61K31/421;C07D277/14;C07D339/02 |
主分类号 |
A61K31/426 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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