This invention provides vectors and methods for the stable introduction of exogenous nucleic acid sequences into the genome of a bird and for expressing said exogenous sequences to alter the phenotype of the bird or to produce desired proteins. In particular, transgenic chickens are produced which express exogenous sequences in their oviducts. Eggs which contain exogenous proteins are also produced.
申请公布号
AT489461(T)
申请公布日期
2010.12.15
申请号
AT19980954994T
申请日期
1998.10.15
申请人
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.;SYNAGEVA BIOPHARMA CORP.
发明人
IVARIE, ROBERT;HARVEY, ALEX;MORRIS, JULIE;LIU, GUODONG;RAPP, JEFFREY C.