A transseptal guidewire (220) for perforating the intra-atrial septum of the heart are disclosed. The transseptal guidewire has an elongated body (222), an end section biased (226) in a curved configuration to define a proximal curve (226a), and a distal section (228) biased in a curved configuration to define a distal curve (228a), the distal curve being oriented in a direction generally opposite that of the proximal curve and the proximal and distal curves occupy the same plane.
