| 发明名称 |
ANTI-GLYPICAN 3 ANTIBODY |
| 摘要 |
<p>An antibody capable of binding to a specific region of glypican 3, as well as a humanized antibody created based on that antibody are disclosed. The anti-GPC3 antibody of the invention has a higher ADCC activity and CDC activity compared with those of a conventional antibody. The antibody of the present invention is useful as a cell growth inhibitor, an anticancer agent and an agent for diagnosis of cancers.</p> |
| 申请公布号 |
PT1674111(E) |
申请公布日期 |
2010.12.15 |
| 申请号 |
PT20050760156T |
申请日期 |
2005.07.08 |
| 申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
NAKANO KIYOTAKA;TAKESHI YOSHINO;JUN-ICHI NEZU;HIROYUKI TSUNODA;TOMOYUKI IGAWA;HIROKO KONISHI;MEGUMI TANAKA;IZUMI SUGO;SHIGETO KAWAI;TAKAHIRO ISHIGURO;YASUKO KINOSHITA |
| 分类号 |
A61K39/395;A61P1/16;A61P35/00;C07K14/47;C07K16/18;C07K16/30;C12N15/09;C12P21/08 |
主分类号 |
A61K39/395 |
| 代理机构 |
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代理人 |
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| 主权项 |
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