发明名称 |
Farmasoytiske preparater innbefattende akryloyl distamycinderivater og topoisomerase I- og II-inhibitorer, produkter omfattende disse samt anvendelse derav. |
摘要 |
The present invention provides the combined use of acryloyl distamycin derivatives, in particular alpha-bromo- and alpha-chloro-acryloyl distamycin derivatives of formula (I), as set forth in the specification, and an antineoplastic topoisomerase I or II inhibitor, in the treatment of tumors. Also provided is the use of the said combinations in the treatment or prevention of metastasis or in the treatment of tumors by inhibition of angiogenesis. |
申请公布号 |
NO329783(B1) |
申请公布日期 |
2010.12.13 |
申请号 |
NO20020006078 |
申请日期 |
2002.12.18 |
申请人 |
NERVIANO MEDICAL SCIENCES SRL |
发明人 |
COZZI PAOLO;GERONI MARIA CRISTINA ROSA;BERIA ITALO |
分类号 |
A61K45/00;A61K31/00;A61K31/401;A61K31/4025;A61K31/4155;A61K31/4178;A61K31/437;A61K31/704;A61K31/7048;A61K45/06;A61P35/00;A61P35/02;A61P43/00 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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