摘要 |
<p>Compound formula I: wherein: X1 and X2 may be either (a) C and O, (b) N and N, or (c) C and NH, where the dotted bonds represents a double bond in the appropriate location; R1 and R2 are independently selected from hydrogen, an optionally substituted C1-7 alkyl group, an optionally substituted C3-20 heterocyclyl group, or an optionally substituted C5-20 aryl group, or may together form, along with the nitrogen atom to which they are attached, an optionally substituted heterocyclic ring having from 4 to 8 ring atoms; RN1 is selected from hydrogen and an optionally substituted C1-4 alkyl group; RC1 is selected from an optionally substituted C1-7 alkyl group, an optionally substituted C3-20 heterocyclyl group, or an optionally substituted C5-20 aryl group; or RN1 and RC1 may together form an optionally substituted C2-4 alkylene group.</p> |
申请人 |
KUDOS PHARMACEUTICALS LIMITED;CANCER RESEARCH TECHNOLOGY LIMITED;FRIGERIO MARK;HUMMERSONE, MARC, GEOFFREY;MENEAR, KEITH, ALLAN;FINLAY, MAURICE, RAYMOND, VERSCHOYLE;GRIFFEN, EDWARD, JOLYON;RUSTON, LINETTE, LYS;MORRIS, JEFFREY, JAMES;TING, ATTILA, KUAN, TSUEI;GOLDING, BERNARD, THOMAS;GRIFFIN, ROGER, JOHN;HARDCASTLE, IAN, ROBERT;RODRIGUEZ-ARISTEGUI, SONSOLES |
发明人 |
FRIGERIO MARK;HUMMERSONE, MARC, GEOFFREY;MENEAR, KEITH, ALLAN;FINLAY, MAURICE, RAYMOND, VERSCHOYLE;GRIFFEN, EDWARD, JOLYON;RUSTON, LINETTE, LYS;MORRIS, JEFFREY, JAMES;TING, ATTILA, KUAN, TSUEI;GOLDING, BERNARD, THOMAS;GRIFFIN, ROGER, JOHN;HARDCASTLE, IAN, ROBERT;RODRIGUEZ-ARISTEGUI, SONSOLES |